Sen. John McCain (R-Ariz.) has been diagnosed with a brain tumor, his office said Wednesday, throwing into doubt when and if he will return to Washington to resume his duties in the Senate.
The Mayo Clinic said doctors discovered a tumor called a glioblastoma following surgery to remove a blood clot above McCainâs left eye last week. The senator and his family are considering a variety of treatment options, including a combination of chemotherapy and radiation, according to the hospital.
McCain, 80 has been away from the Senate this week, recovering from the surgery and undergoing tests. His office issued a statement describing him âin good spiritsâ and noting that his underlying health is excellent â but not indicating when he will return to the Senate.
Glioblastoma is an aggressive type of brain cancer, and the prognosis for this kind of cancer is generally poor. The late senator Edward Kennedy survived less than 15 months after his was found.
McCainâs significance inside Congress is hard to overstate â and his absence, however long, will reverberate across the Capitol.
The Arizonanâs illness leaves Senate Majority Leader Mitch McConnell (R-Ky.) â and by proxy President Trump, who has openly mocked the Arizona senator â with just 51 votes, the barest of majorities at a time when Republicans are divided on such issues as health care, taxes and defense spending.
McCainâs void will also deprive the Senate of its moral conscience on many key issues, particularly in the ongoing investigation of the Trump campaignâs potential involvement in Russian meddling in the 2016 campaign.
Colleagues from both parties reacted swiftly to McCainâs announcement with sadness and encouragement. Trump exhorted McCain to âget well soonâ and declared the senator a âfighter.â
McConnell said: âI know that he will face this challenge with the same extraordinary courage that has characterized his life. The entire Senate familyâs prayers are with John, Cindy and his family, his staff, and the people of Arizona he represents so well.
âWe all look forward to seeing this American hero again soon.â
McCain, a prisoner of war in Vietnam and a two-time presidential candidate, is known for his unfiltered opinions and willingness to buck Republican party orthodoxy. Along with Sen. Lindsey O. Graham (R-S.C.), perhaps his closest friend in the Senate, McCain has become one of Trumpâs leading Republican critics, particularly on issues of foreign policy and national security.
Sen. John Hoeven (R-N.D.) said the news of McCainâs diagnosis was announced during a meeting between GOP senators and White House staff on health care. Hoeven said the news left the group in âstunned disbelief.â
âIt was very emotional,â Hoeven said. âI think for all of us heâs a special person.â
Hoeven said Graham told them in the meeting that he had spoken with McCain earlier in the evening. âHe wants to get back and get to work,â Hoeven said of McCain, âwhich is just what you would expect.â
McCain has staunchly defended Trumpâs national security team â he has particular respect for Defense Secretary Gen. James Mattis and national security adviser H.R. McMaster. But he has criticized the president for campaigning on a promise to fortify the countryâs defenses without, in his view, devoting enough money to the task.
McCain has also criticized Trumpâs apparent affinity for Russia and its president, Vladimir Putin, warning that Russia is an enemy that should not be trusted and becoming one of the earliest Republicans to lend his support to a congressional investigation of Russiaâs ties to the election.
âJohn McCain has always been a warrior. Itâs who he is,â said House Speaker Paul D. Ryan (R-Wis.). âI know John is going to fight this with the same sheer force of will that has earned him the admiration of the nation. And all of us, not as Republicans or Democrats, but as Americans, are behind him. The prayers of the whole House are with Senator McCain and his family.â
McCainâs formal title is chairman of the Senate Armed Services Committee, but McConnell essentially deputized him after his second presidential bid, in 2008, to run all national-security issues for Senate Republicans.
But his standing â from his stature borne of overcoming torture in Vietnam to his staunch denunciations of Trump as a candidate and as president â reaches far across the aisle as an iconic figure as beloved by Democrats as Republicans.
Almost every major bipartisan deal of the last 15 years has come with McCainâs backing, on issues ranging from immigration to outlawing torture to the Senateâs internal rules.
Democrats line up to travel with McCain overseas because foreign leaders treat him as if heâs a prime minister, winning audiences that are usually reserved for a secretary of state.
His fights with fellow senators have been legendary, but so have his deal making skills.
âHeartbreaking news,â wrote Sen. Chris Murphy (D-Conn.) on Twitter. He said he âtraveled the worldâ with McCain and âlearned a lot from him. Murphy added: âthere is no one tougher.â
In a written statement she posted on Twitter, McCainâs daughter, Meghan McCain, said the news of her fatherâs illness has âaffected every one of us in the McCain family.â She said they live with âanxiety about what comes next,â which they have endured before. McCain has a history of melanoma, a dangerous form of skin cancer.
She added, âit wonât surprise you to learn that in all this, the one of us who is most confident and calm is my father. He is the toughest person I know. The cruelest enemy could not break him.â
McCainâs absence could complicate the fate of the annual National Defense Authorization Act, massive legislation that McCain has played an outsized role in shepherding through Congress since he took over as chairman of the Senateâs Armed Services Committee in 2015.
From that perch, McCain has made a name for himself attempting to hold contractors to account over stalled projects while driving an overhaul of the acquisition process. He has pushed for greater investments to improve the quality and availability of materiel and training, an expansion of the American military footprint abroad, particularly in hotspots like Afghanistan and Iraq, and an unprecedented focus on improving the countryâs ability to safeguard against cyber threats and hackings.
McCain is at times a partisan and at other times ready to buck his party. He was relentless in his criticism of former president Barack Obamaâs understanding of national security, accusing him of compromising the nationâs security by making nuclear deals with Iran and pulling troops out of Afghanistan and Iraq. But he was also open to working with the president to explore closing the detention facility at Guantanamo Bay. That effort ultimately failed.
McCainâs absence from the Senate this week came as GOP leaders struggled to bring their failing push to rewrite the Affordable Care Act to a conclusion. Leaders had intended to vote on a bill this week but postponed their plans late Saturday after McCain said he would be out recovering from the surgery to remove the blood clot.
On Monday, McConnell scrapped plans to vote on the bill altogether once it became clear it would not have the support to pass even with McCain in town to vote. McCain had voiced skepticism about the GOP ârepeal and replaceâ plan. It was unclear that he would ever get to yes on it.
About 12,400 new cases of glioblastoma are expected in 2017, according to the American Brain Tumor Association. It is the most common of all malignant brain tumors, and a tumor that more commonly occurs in older adults than younger people.
Matthias Holdhoff, an associate professor at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, said the first step after a diagnosis is to surgically remove as much of the glioblastoma as possible. But that can be difficult; it is a tumor that spreads through extensions into the tissue, âmore like a mesh work than a lump.â
âItâs not just a matter of the cancer, but where it is and what itâs doing to the patient,â said Washington oncologist Frederick Smith, speaking generally about glioblastomas and not specifically about McCainâs case. A blood clot over the eye tends to indicate the tumor was in the brainâs frontal lobe, which controls cognition among other things, he said.
Again speaking generally of patients with this diagnosis, they âmight be fine for a number of months or even years.â But they are never cured.
Lenny Bernstein, Laurie McGinley, Kelsey Snell and Ed OâKeefe contributed to this report.